PKM and ovarian carcinoma: Li et al. have integrated 1198 mtDEPs derived from mitochondrial proteomics, 205 DEPs from whole-tissue proteomics, and 20115 genes from transcriptomics across 419 ovarian cancer samples in human ovarian cancers [63] (Figure 2), which finds that several energy metabolism-related enzymes are upregulated, including PFKP and PKM in aerobic glycolysis; CS, PDHB, IDH2, and OGDHL in the TCA pathway; and UQCRH in the OXPHOS pathway.