C57BL/6J mice that underwent I/R (1.5 h/24 h) exhibited obvious nerve dysfunction and serious brain infarction (Figures 1(a)–1(c)), accompanied by elevated TUG1 and St8sia2 and reduced miR-3072-3p expression at the mRNA level (Figures 1(d)–1(f)). Here, TUG1 is linked to brain infarction.