Naphthalene-tripeptides containing alpha-aminoisobutyric acid or alanine have shown various potential uses in combating cancer and bacterial infections.88 The UAA p-acetyl phenylalanine (pAcF) can be integrated with an EGFR targeted, elastin-like polypeptide nanomaterials in the presence of reactive amino acids to produce bio-orthogonal ketone for attachment of doxorubicin, and thus produced nanomaterials are proven to have considerably higher cytotoxicity than non-target controls in several lines of cancer cells.61 This evidence concerns the gene EGFR and cancer.