Reducing the overexpression of miR-155 modulates the expression of cytokines such as IL-1 and CXCL8 (69); miR-155-enriched exosomes slow down cardiac fibroblast proliferation by downregulating Son of Sevenless 1 (SOS1) expression—which is also involved in the regulation of inflammation (70)—and can promote inflammation and atherosclerotic lesions by increasing STAT3 and NF-κB via targeting Suppressor of Cytokine Signaling 1 (SOCS1) expression (16). This evidence concerns the gene SOCS1 and Atherosclerotic lesion.