CAV1 and Ventricular arrhythmia: Atrial fibrillation was associated with decreased CAV1 in right and left atria (p = 0.03); Loss of CAV1 leads to cSrc tyrosine kinase activation, gap junction remodeling, and ventricular arrhythmia, slowing left ventricular conduction velocity, and increasing ventricular arrhythmia inducibility (32).