ACTG2 and Alzheimer disease: Additionally, Wang et al. found that linc01278 plays a role in AD and confirmed that the linc01278/miR-500b-5p/ACTG2 axis is the most relevant target gene through advanced bioinformatics analysis such as GEO2R analysis, gene ontology (GO), pathway enrichment analysis, and protein-protein interaction (PPI) network (100).