CDKN2B and coronary artery disorder: This is consistent with the study by Li et al. They confirmed the ceRNA network of CDKN2B-AS1 in coronary heart disease and found that CDKN2B-AS1 upregulates protein tyrosine phosphatase non-receptor type 7 (PTPN7) by absorbing miR-126-5p and inhibits the PI3K-Akt pathway, thus hindering the proliferation of and accelerating apoptosis of VSMCs induced by oxidized low-density lipoprotein (ox-LDL) (80).