Sixty days after hHTX, GATA2 expression was significantly downregulated in grafts subjected to 12 h of ischemia, but this effect was reversed when donors had received S-NO-HSA (−6.00 ± 0.45 vs. −7.188 ± 0.5; 12 h-S-NO-HSA-hHTX vs. 12 h-control-hHTX: p = 0.0008; normalized expression to ACTB). This evidence concerns the gene GATA2 and ischemia.