Additionally, the protein expression of SETDB1, BATF3, and PD-L1 was diminished while FOSB expression was upregulated in the presence of sh-SETDB1+OE-NC while opposite results were detected in the tumor tissues of mice treated with sh-SETDB1+OE-BATF3 (Figure 5(d)). This evidence concerns the gene BATF3 and neoplasm.