For example, Yang et al. determined that CTF1 was able to enhance tissue regeneration in the context of liver cirrhosis by promoting cellular proliferation and angiogenesis (Yang et al., 2008), consistent with evidence that CTF1 overexpression using an adenoviral vector can improve liver function and survival associated with small-for-size grafts (Song et al., 2008). Here, CTF1 is linked to cirrhosis of liver.