Interestingly, neutrophil elastase was significantly higher in patients who developed severe AKI (242.6 ng/mL [IQR: 173.1-368.9]) compared to patients who did not (132.4 ng/mL [IQR: 95.8-218.4]; p = 0.029) (Supplemental Figures S2 and S3). This evidence concerns the gene ELANE and acute kidney injury.