PROS1 and COVID-19: Gaining deep insights into all those viral protein in silico studies of SARS-CoV-2, we infer that curcumin can bind and interact with several target viral proteins that assist in viral attachment (S protein), replication (nsp12, nsp9), posttranslational protein cleavage/modification (Mpro), and host immunity evasion (nsp15), suggesting that curcumin/curminoids provide a promising hit against COVID-19 even without any additional demonstration (in vitro and in vivo validation).