NPPB and Alzheimer disease: Furthermore, the ROC curve analysis revealed that all indicators had high diagnostic value, of which AD screening scale and TN-C expression level could reach a 100% sensitivity for the diagnosis of AAD, and the specificity of TN-C expression level was as high as 98.25%, suggesting a promising diagnostic value of AD, TN-C, D-D, NT-proBNP, and blood coagulation function indicators for the diagnosis of AAD.