While all the genes encoding CENPs seemed to be universally upregulated in ESCC (logFC > 0; Figures 1(a)–1(c)), the gene encoding CENPC was downregulated in GSE38129 and GSE20347 (logFC < 0; Figures 1(a)–1(c)). This evidence concerns the gene CENPC and esophageal squamous cell carcinoma.