TTK and esophageal squamous cell carcinoma: The results of differential expression analysis showed that BRCA1, BUB1B, and TTK were significantly upregulated in ESCC tissues based on the TCGA, GSE38129, and GSE20347 datasets, at the same time notable overexpressed in ESCC cell lines based on the GSE23964 dataset (FDR < 0.05 and P < 0.05; Figures S3(b)–S3(e)).