GLP1R and prediabetes syndrome: Glucagon-like peptide-1 (GLP-1) receptor agonists such as liraglutide had been proved to sustain weight loss in obese patients and were associated with the reversal of prediabetes to normoglycemia during 1–2 years of follow-up (1) and another study showed that 3.0 mg of liraglutide was an adjunct to diet and exercise, associated with reduced body weight and improved metabolic control (27).