CRP and vitamin D deficiency: Using correlation analysis, chi-square test, and univariate logistic regression analysis, HBI ≥ 8; ileocolonic (L3); penetrating disease(B3); low levels of TC, HDL-C and LDL-C; and high levels of ESR, hs-CRP, SAA, WBC, and PLT were defined as independent risk factors for severe vitamin D deficiency in patients with CD.