TNF and diabetes mellitus: The expression levels of mRNA of inflammatory factors such as IL-6, IL-1β, and TNF-α in myocardial tissues of DM rat model were detected by qRT-PCR in each group, and the changes were as follows: compared with DCM group, the mRNA levels of inflammatory factors such as IL-6, IL-1β, and TNF-α in myocardial tissues of rats in S2 and S3 groups were significantly lower (P < 0.05); the mRNA levels of inflammatory factors such as IL-6, IL-1β, and TNF-α in myocardial tissues of rats in S3 group were lower than those in S2 group (P < 0.05) (see Figure 6).