We also found that the expression of lncRNA MSTRG.14019.1 was significantly increased at 12 h post infection (hpi) with H5N1 AIV, which is contrary to the expression trend of CSE1L. Thus, these results suggest that lncRNA MSTRG.14019.1 may inhibit the replication of H5N1 AIV by inhibiting the expression of CSE1L. This evidence concerns the gene CSE1L and infection.