DCT and neoplasm: Combination therapy of VEE-TRP-2 with antagonist anti-CTL antigen-4 (CTLA-4) or agonist anti-glucocorticoid-induced tumor necrosis factor receptor (GITR) monoclonal antibodies (mAbs) led to tumor regression of 50 and 90% of mice, respectively (Avogadri et al., 2014).