For example, host epidermal growth factor receptor (EGFR) was reported to interact with NTCP and mediate HBV internalization (Iwamoto et al., 2019), a finding that potentially accounts for the low rate of infection in the HepG2 cell line, in which EGFR expression is undetectable (Zhao et al., 2013). The gene discussed is SLC10A1; the disease is infection.