In recent years, advances have been made in BC treatment options including immunotherapy, cyclin-dependent kinase 4/6 (CDK4/6) inhibitors, tyrosine kinase inhibitors (TKIs), clustered regularly interspaced short palindromic repeats (CRISPR), microRNAs (miRNAs), use of already available drugs for different diseases for treating BC (drug repurposing), nanotechnology-based treatments, and electrochemotherapy (ECT). The gene discussed is CDK4; the disease is breast cancer.