TGFBR2 and Familial adenomatous polyposis: Interestingly, our data showed a clear predominance of CPGs related to gastrointestinal/colorectal cancer risk, such as familial adenomatous polyposis one and 2 (APC and MUTYH), nonpolyposis colorectal cancer hereditary types 1 (MSH2) and 6 (TGFBR2), Li-Fraumeni syndrome 2 (CHEK2), and Diamond-Blackfan anemia 1 (RPS19).