CDKN1A and acute promyelocytic leukemia: We observed after 2 months of standard treatment with all-trans retinoic acid and idarubicin, upregulation of ABCB1, CDH1, CDKN1A, TNFRSF1A, and epigenetic regulators like ATM, DNMT1, HDAC1, polycomb complex components EED, and SUZ12 in all APL patients.