Immunoprecipitation of whole-cell lysates with an antiserum against SMYD3 or BLM, followed by immunoblotting, showed that SMYD3 is a molecular partner of BLM in CRC cells (Figs. 3B, 4) and in GC cells (Appendix Fig. S2). The gene discussed is SMYD3; the disease is colorectal carcinoma.