Similarly, AKT1 and HSP90 (HS90A), which are also known SMYD3 targets and are included in Reactome pathways clustering in cancer hallmarks “tumor-promoting inflammation” and “resisting cell death”, respectively [24], [26], also contain various P-tripeptides (Fig. 4 and Appendix Tables S4 and S8). Here, AKT1 is linked to cancer.