It is confirmed that kinase inhibitor treatment increased cell apoptosis in FGFR4-mutant rhabdomyosarcoma (RMS) cell lines, which is consistent with increased SubG1 fraction and high level of activated caspase-3, suggesting the strong dependency of RMS on FGFR4 (Taylor et al., 2009). This evidence concerns the gene FGFR4 and rhabdomyosarcoma.