The expression of SRSF3 in different tumor and normal tissue types were evaluated by utilizing the TCGA database and the results showed that the expression of SRSF3 was upregulated relative to normal tissue types in 9 out of 33 pan-cancers, namely, CHOL, COAD, ESCA, GBM, HNSC, LIHC, LUAD, LUSC, and STAD. This evidence concerns the gene SRSF3 and cancer.