The consequence showed that the correlation between SRSF3 expression level and TMB exists significance (P <0.05) in 15 out of 33 cancer types, namely, ACC, BLCA, BRCA, COAD, HNSC, LGG, LUAD, LUSC, OV, READ, STAD, TGCT, THCA, THYM, and UCEC, of which STAD had the highest coefficients while THYM had the lowest coefficients (Supplementary Figure 2A). The gene discussed is SRSF3; the disease is cancer.