We found endothelial cell marker VE-cadherin was downregulated in group A compared with group B, whereas mesenchymal cell markers vimentin and MMP9, were upregulated in group A compared with group B. Vascular cell adhesion molecule-1 (VCAM-1), an endothelial activation marker, was also upregulated in Group A. In addition, overexpression of mesenchymal cell markers FN, vimentin, COLI, and serpine1 were detected in DLBCL patients compared with healthy donors (Figures 1A, B). Here, SERPINE1 is linked to diffuse large B-cell lymphoma.