The mRNA and protein levels of CAMK1D were notably upregulated in glioma cells transfected with CAMK1D plasmids and were downregulated in glioma cells transfected with siCAMK1D, compared to the pcNC (transfected an empty vector) and siNC (transfected a scramble siRNA) (Figures 4A, B). This evidence concerns the gene CAMK1D and central nervous system cancer.