Western blot analysis showed that overexpression of CAMK1D downregulated p-Akt, p-mTOR, and p-P70S6K, and decreased p-Akt/Akt, p-mTOR/mTOR, and p-P70S6K/P70S6K ratios in glioma cells (Figure 7A). Here, AKT1 is linked to central nervous system cancer.