EGFL7 and lung cancer: After treatment with the DNA demethylating agent 5-Aza-CdR, EGFL7 mRNA and miR-126 were significantly upregulated in both SPC-A1 and H1299 lung cancer cell lines (P < 0.05, Figure 3), while no significant difference of EGFL7 mRNA expression was observed in BEAS-2B (Figure 3).