CTNNBL1 and chronic myelogenous leukemia, BCR-ABL1 positive: After the identification of Philadelphia chromosome as a hallmark of chronic myelogenous leukemia (CML), Tanzer et al. were the first to report a patient without Philadelphia chromosome or increased marrow fibrosis but high Leucocyte- or Neutrophil- Alkaline Phosphatase (LAP or NAP) score.