NFKB1 and ischemic stroke: Therefore, we proposed that ta-VNS might improve the inflammatory environment of the white matter by inhibiting the activation of the TLR4/NF-κB and MAPK/NF-κB signaling pathways, thus affecting endothelial cell function and promoting neurovascular unit (NVU) regeneration in the white matter and promoting swallowing function recovery after ischemic stroke.