According to the results, the fold changes of activation of CD8+ T cells, TEM subsets, and TEMRA subsets after childbirth were markedly higher in Group 1 than in Group 2 (p = 0.05, p = 0.01, p < 0.0001, Figure 3D), implying that postpartum hepatitis flare in immune-tolerant HBV patients may be correlated with changes in immune function. Here, CD8A is linked to hepatitis A virus infection.