CRP and systemic lupus erythematosus: Many of the identified autoantigens are commonly associated with systemic autoimmune diseases, such as systemic lupus erythematosus, including antibodies specific for nuclear proteins, C-reactive protein, hemocyanin, complement C1q, and β2-microglobulin (50, 51), in cIIAKO mice, compared to floxed control mice.