CD8A and neoplasm: Considering the significant correlation between the risk score and CD8 T cell and the important role of m6A methylation in impairing the anti-tumor ability of CD8 T cell, we next analyzed the expression of the CD8 T cell-related IFN-gamma pathway markers and m6A regulators in low- and high-risk groups and found most of them were significantly associated with the risk score (Figures 9B, C).