Next, we conducted LASSO Cox regression with the 128 genes and obtained 11 robust genes (KLRB1, GZMH, SLC16A3, IMPDH1, IL15RA, MSC, S100A9, ST6GALNAC4, DAB2, ADA, SLC1A5) that were significantly correlated with the OS of HCC patients from TCGA-HCC dataset. Here, S100A9 is linked to hepatocellular carcinoma.