DCT and neoplasm: Herein, we have generated an oncolytic adenovirus (OAd) encoding either the model protein chicken ovalbumin (OVA) or the more clinically relevant tumor antigen murine tyrosinase-related protein 2 (TRP2); then we have carefully characterized the T-cell immune profile in mice pre-immunized either with the OAd encoding the TAs or with PeptiCRAd.