Neurodegenerative processes, detrimental and protective role in myelin injuries, enhancement in excitatory transmission, neuronal production and modulation of synaptic activity, neuro-inflammation, transport of endocannabinoid N-arachidonoylethanolamine, aminopeptidase CD13 and the lactate transporter monocarboxylate transporter-1 (MCT-1) markers, neurodegeneration in amyotrophic lateral sclerosis, TNF production. This evidence concerns the gene CPQ and amyotrophic lateral sclerosis.