Among these, SCA17 (OMIM#607136) is caused by CAG/CAA repeat expansions in the coding sequence of the TATA box-binding protein (TBP; OMIM *600075) gene and is associated with cognitive decline, psychiatric features, and HD-like symptoms (Koide et al., 1999; Toyoshima et al., 2005/2019). This evidence concerns the gene TBP and Mental deterioration.