Besides, subgroup analysis revealed that patients with high CISD2 expression showed poorer OS in cases with G3 (P = 0.005), G4 (P = 0.026), astrocytoma (P = 0.001), and glioblastoma (P = 0.026) (Figures 2(c)–2(f)). The gene discussed is CISD2; the disease is glioblastoma.