At an in vitro level (with the exception of Campesterol), these phytochemical compounds have been reported to stabilize and accumulate p53 in the nuclei of different cancer cell lines, possibly through the disruption of mortalin-p53 complexes (Wang et al., 2014; Nigam et al., 2015; Bhargava et al., 2018; Garg et al., 2019; Pham et al., 2019). This evidence concerns the gene HSPA9 and cancer.