Although previous GWAS studies have suggested that ULK4 is a risk locus for multiple myeloma and interindividual diastolic blood pressure variation, emerging evidence also supports the idea that ULK4 genetic variants may cosegregate people with multiple neuropsychiatric disorders (Levy et al., 2009; Broderick et al., 2011). This evidence concerns the gene ULK4 and AL amyloidosis.