A recent study also reported that patients with a microdeletion of the ULK4 gene and a microduplication of the BRWD3 gene manifested core features of ciliopathy such as psychomotor delay, epilepsy, autistic features, hearing loss, obesity, minor facial dysmorphisms, peculiar ear malformations, and skeletal abnormalities (such as dorsal kyphosis and/or valgus knees and flat feet) (Tassano et al., 2018). This evidence concerns the gene ULK4 and ciliopathy.