TGFB1 and nasopharyngeal carcinoma: In the context of TDEs inducing TGF-β1 expression in T cells, nasopharyngeal cancer (NPC)-derived EVs recruited Treg cells, inducing TGF-β1 release, and converting CD4+CD25− T cells to CD4+CD25high T cells (Mrizak et al., 2015).