APOE and atherosclerosis: Accordingly, we established in vivo C. pneumoniae infection-induced atherosclerosis models using ApoE‐/‐ and ApoE‐/‐TLR2‐/‐ mice, and found that the levels of ROS in atherosclerotic lesions were reduced by approximately 48.77% in ApoE‐/‐TLR2‐/‐ mice with C. pneumoniae infection compared with C. pneumoniae-infected ApoE‐/‐ mice (Figures 8A,B).