IL6 and viral infectious disease: Any deviation in expression of cytokines involving elevation in interferon regulatory factor 3 (IRF3) (crucial transcription factor during viral infection) (X. Li et al., 2015), IFN-γ (regulates viral multiplication) (Paul-Samojedny et al., 2011), pro-inflammatory IL-1α (Katila et al., 1999), IL-1β (Sasayama et al., 2011), IL-6 (Kalmady et al., 2014; Frydecka et al., 2015) and anti-inflammatory IL-10 (Gao et al., 2014), along with elevated mRNA levels of CRP, IL-6, IL-1β, TNF-β, and TGF-β, have been reported in SCZ individuals (Kroken et al., 2019).