MFN1 and female infertility: In addition to DRP1, several studies demonstrated that the conditional knock-out of mitofusin 1 or 2 (MFN1 or MFN2) leads to male or female infertility in mice models (Varuzhanyan et al., 2019; Zhang et al., 2019; Chen et al., 2020; Wang et al., 2021).