CD8A and neoplasm: TMEsubgroup2 evinced high levels of the antitumor immunity (activated CD8+ T cells, NK cells, and NKT cells), pro-tumor immunity (Treg, MDSC, and Th2 cells), and stromal cells (endothelial cells, fibroblasts, and Schwann cells), which indicated that both cytolytic and inhibitory immune activities were activated in these patients.