MAPT and diabetes mellitus: There was no statistical significance in years of education, preoperative MMSE score, history of diabetes, or history of hypertension (P > 0.05), while the differences in sex, age, Serum TC, TG, LDL-C, HDL-C, CSF Aβ40, Aβ42, t-Tau, p-Tau, Aβ42/Aβ40, Aβ42/t-Tau, Aβ42/p-Tau, Aβ40/t-Tau, Aβ40/p-Tau, t-Tau/p-Tau, and Postoperative MDAS score were statistically significant (P < 0.05).