Interestingly, three studies summarized evidences that the association between SARS-COV-2, ACE2 and the renin/angiotensin system negatively affects the skeletal muscle, increasing muscle weakness and hindering the full recovery of positive-COVID-19-individuals (Ferrandi et al., 2020; Gonzalez et al., 2020; Yamamoto et al., 2020). This evidence concerns the gene ACE2 and COVID-19.