Other patients with drug-resistant focal epilepsy and mutations in SCN1A, CNTNAP2, STBXP1 genes were not seizure-free after epilepsy surgery regardless of lesional status (including HS, focal cortical dysplasia, encephalomalacia present on MRI) [3], [8], [9], [14], [15]. This evidence concerns the gene CNTNAP2 and Focal cortical dysplasia.