SCN8A and epilepsy: An epilepsy gene panel (Invitae, San Francisco, CA; sequence analysis and deletion and duplication testing of the 181 genes) at the time of pre-surgical evaluation identified four variants of uncertain significance (VUS) in CACNA2D2, SCN8A, SYNJ1 and SZT2; therefore, his genetic testing was deemed not conclusive for a monogenic epilepsy disorder at that time.