FN1 and Miyoshi myopathy: More recently, Jargidar et al. (28) tested epithelioid, biphasic and sarcomatoid MM cell types in vitro and found that fibronectin (FN) and homologous cell-derived extracellular matrix (hcd-ECM) treated substratum differentially affected the above phenotypes; 3D MM spheroid invasion was higher in fibronectin-collagen matrices in the epithelioid and biphasic cells, while 3D cell cultures of epithelioid and sarcomatoid MM cells in fibronectin-collagen showed a higher contractility compared to hcd-ECM-collagen.