TNF and COVID-19: So, a significant increase in cytokines such as IL-2, IL-7, IL-10, monocyte chemoattractant protein-1 (MCP1), granulocyte colony-stimulating factor (GSCF), macrophage inflammatory protein 1A (MIP1A), IFN-γ-induced protein-10 (IP10), and tumor necrosis factor-α (TNF-α) was characteristic to severe COVID-19 patients which may have hugely damaging effects.