NRBP2 and cancer: Moreover, the immunofluorescence staining indicated that overexpression of NRBP2 in cancer cells significantly reduced the fluorescence intensity of Arg1 in the macrophages (oe-NC vs. oe-NRBP2: TPC-1: 49.31 vs. 18.42, p < 0.0001; CAL62: 42.16 vs. 13.76, p < 0.0001) (Figure 3(c)).